Product Name:
Human Proto-oncogene Tyrosine-Protein Kinase Fyn (FYN) ELISA Kit
Cat.#:
JL17920
Regulatory Status:
Alternative:
SLK; SYN; c-Fyn; Src-like kinase；FYN Oncogene Related To SRC/FGR/YES
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.156-10ng/mL
Sensitivity:
0.074ng/mL
Specificity:
This kit recognizes Human fyn in samples. No significant cross-reactivity or interference between Human fyn and analogues was observed.
Sample Type:
Tissue homogenates;cell lysates and other biological fluids
Assay Procedure:
Research Area:
Cancer
Size & Price: 
Product Datasheets
Instruction: 
| fyn
Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that is encoded by the FYN gene.Fyn is a 59-kDa member of the Src family of kinases typically associated with T-cell and neuronal signaling in development and normal cell physiology. Disruptions in these signaling pathways often have implications in the formation of a variety of cancers. By definition as a proto-oncogene, Fyn codes for proteins that help regulate cell growth. Changes in its DNA sequence transform it into an oncogene that leads to the formation of a different protein with implications for normal cell regulation.
| Repeatability
Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%| Recovery
The recovery of Human fyn spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.| Sample Type | Range(%) | Average Recovery(%) |
| Tissue Homogenates(n=8) | 90-105 | 102 |
| Cell Lysates(n=8) | 96-108 | 106 |
| Linearity
Samples were spiked with high concentrations of Human fyn and diluted with Universal Diluent to produce samples with values within the range of the assay.| Tissue Homogenates(n=4) | Cell Lysates(n=4) | ||
| 1 : 2 | Range (%) | 85-96 | 90-110 |
| Average (%) | 93 | 96 | |
| 1 : 4 | Range (%) | 87-108 | 105-115 |
| Average (%) | 98 | 109 |
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